Avodart® (Dutasteride 0.5mg): The first dual-acting 5 alpha-reductase inhibitor for benign prostatic hyperplasia (BPH), approved by the FDA. Avodart® reduces the 2 enzymes responsible for the conversion of testosterone to DHT – which is a primary concern in hair loss. Propecia (Finasteride) only blocks one enzyme, by blocking both Avodart's results so far have shown to be better for halting hair loss and re-growing hair in men suffering from alopecia.
Dutasteride, a 2nd generation 5 alpha-reductase inhibitor, is the first and only drug to inhibit both the type 1 and type 2 enzymes responsible for the conversion of testosterone to DHT (dihydrotestosterone), the main cause of prostate enlargement. Dutasteride's dual inhibition has been found to decrease levels of DHT by 90 percent at 2 weeks and 93 percent at 2 years.
By lowering DHT levels, dutasteride reduces the size of an enlarged prostate. This reduction in prostate volume was seen as early as 1 month with reductions continuing during treatment. Reducing the size of the enlarged prostate is beneficial for relieving urinary obstruction and improving urinary flow. While improving urinary symptoms Dutasteride also reduces the risk of AUR (the sudden complete inability to urinate), and BPH-related surgery, which are two potential long-term critical consequences of BPH. The telling phase III study data were published in the journal Urology.1
"With dutasteride, we now have a medicine that reduces the production of DHT by more than 90 percent, helping to shrink the prostate," said Claus Roehrborn, MD, a principal trial investigator and professor and chairman of the Department of Urology at the University of Texas Southwestern Medical Center in Dallas , Texas . "By taking dutasteride, patients can improve urinary symptoms and reduce their risk of suffering from acute urinary retention - where you suddenly can't urinate at all - or needing BPH-related prostate surgery."
After six month of treatment, the hair counts measured in a 1 inch diameter circle improved by about ~96 hairs with 0.5mg Dutasteride, compared to about ~72 hairs with 5mg Finasteride. The hair counts increased significantly with an increase in dosage with the biggest gain being ~108 hairs with a dose of 2.5mg Dutasteride. So compared to 5mg Finasteride (Proscar), 2.5 mg Dutasteride grew about 1.5 times as many hairs. This is why there is so much excitement with Dutasteride for hair loss treatment in men.
Free Avodart Prescription Consultation. Propecia-Proscar pharmacy offers a free prescription consultation for the direct online purchase of Avodart. Therefore a prior prescription is not necessary to order Avodart to treat hair loss.
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